LRP5 rabbit pAb - ES15106

LRP5 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15106-50, ES15106-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human LRP5 AA range: 1047-1097

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4041

Human SWISS Prot NO: O75197

Subcellular Location: Membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Chaperoned to the plasma membrane by MESD.

Research Use Only