LRP6 (Phospho Thr1479) Rabbit Polyclonal Antibody - RA26924

LRP6 (Phospho Thr1479) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26924-50, RA26924-100

Citations, Manuals and MSDS Available upon request.

Background: LDL receptor related protein 6 (LRP6) Homo sapiens This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000

Alternative Names: Low-density lipoprotein receptor-related protein 6 (LRP-6)

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 4040

Protein MW (KDa): 177

SWISS: O75581

Source: Rabbit

Research Use Only