LRPAP1 Polyclonal Antibody-BS7471

LRPAP1 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS7471-50, BS7471-100

Swiss-Prot: P30533

Host: Rabbit

LRPAP1 Polyclonal Antibody-BS7471

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: Low density lipoprotein receptor-related protein associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LRPAP1 polyclonal antibody detects endogenous levels of LRPAP1 protein.

Bioworld Molecular Weight: ~41 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of LRPAP1 polyclonal antibody, Immunohistochemistry (IHC) analysis of LRPAP1 polyclonal antibody in paraffin-embedded Rat Testis tissue.

Alternative Name: A2MRAP;
A2RAP;
Alpha 2 macroglobulin receptor associated protein;
Alpha 2 MRAP;
Alpha-2-macroglobulin receptor-associated protein;
Alpha-2-MRAP;
AMRP_HUMAN;
HBP44;
Lipoprotein receptor associated protein;
Low density lipoprotein receptor related protein associated protein 1;
Low density lipoprotein receptor-related protein-associated protein 1;
Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein;
Low density lipoprotein related protein associated protein 1;
Lrpap1;
MGC138272;
MRAP;
RAP;

Immunogen: Recombinant full length Human LRPAP1.

Modification: Unmodified

Conjugate: Unconjugated