LRRC41 rabbit pAb - ES2726

LRRC41 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2726-50, ES2726-100

Citations, Manuals and MSDS Available upon request.

Background: caution:It is uncertain whether Met-1 or Met-23 is the initiator., domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x (3)-C-x (3)-[AILV]., function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Translation N-terminally extended., similarity:Contains 7 LRR (leucine-rich) repeats., subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS (LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2.,

Alternate Name: LRRC41; MUF1; PP7759; Leucine-rich repeat-containing protein 41; Protein Muf1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human LRRC41. AA range:391-440

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 80kD

Human Gene ID: 10489

Human SWISS Prot NO: Q15345

Subcellular Location: nucleus, cytoplasm, membrane,

Research Use Only