LRRFIP1 Monoclonal Antibody-MB0034

LRRFIP1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB0034-50, MB0034-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q32MZ4

Host: Mouse IgG1

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:1000

Background: Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins

Bioworld Molecular Weight: Predicted band size:89KDa
Observed band size:160KDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western BlotDetection of LRRFIP1 in Raji, C2C12, MCF7&Jurkat cell lysates using LRRFIP1 antibody (1:1000 diluted).

Alternative Name: GC-binding factor 2; TAR RNA-interacting protein; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1

Immunogen: Recombinant full length Human LRRFIP1.

Conjugate: Unconjugated

Modification: Unmodified