Product Description

LRRK2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10979-20, BT-AP10979-50, BT-AP10979-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

Research Areas: Neuroscience

Target Protein: LRRK2

Applications: IHC-p, IF

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Leucine-rich repeat serine/threonine-protein kinase 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q5S007; Mouse: Q5S006

Synonyms: Leucine-rich repeat serine/threonine-protein kinase 2;EC 2.7.11.1;Dardarin

GeneID: Human: 120892

Research Use Only