Lsk Monoclonal Antibody - RA11631

Lsk Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11631-50, RA11631-100

Citations, Manuals and MSDS Available upon request.

Background: megakaryocyte-associated tyrosine kinase (MATK) Homo sapiens The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Condition: Antibody are purified by protein G affinity chromatography. Liquid in PBS containing 50% glycerol and 0.03% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; FCM; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 4145

SWISS: P42679

Source: Mouse

Research Use Only