Product Description

LSM4 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8083-50, BS8083-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9Y4Z0

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB 1:500 - 1:1000

Background: Sm and Sm-like (LSm) proteins form donut shaped heptameric complexes that are involved in various steps of RNA metabolism. Lsm proteins facilitate RNA protein interactions and structural changes that are required during ribosomal subunit assembly. LSm4, also called U6 snRNA-associated Sm-like protein or Glycine-rich protein (GRP), binds specifically to the 3'-terminal U-tract of U6 snRNA. Human LSm4 localizes to the cytoplasm in small, discrete foci. These foci are also the localization site for the mRNA decapping enzyme Dcp1/2 and the exonuclease, Xm1.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LSM4 polyclonal antibody detects endogenous levels of LSM4 protein.

Bioworld Molecular Weight: ~ 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of LSm4 expression in K562 (A), NIH3T3 (B) whole cell lysates.

Alternative Name: U6 snRNA-associated Sm-like protein LSm4; Glycine-rich protein; GRP; LSM4

Immunogen: Synthetic peptide, corresponding to Human LSM4.

Conjugate: Unconjugated

Modification: Unmodified