Product Description

LTB4DH (L105) Polyclonal Antibody

Catalogue Numbers: BS3885-50, BS3885-100

Sizes: 50µl, 100µl

Alternative Name: Prostaglandin reductase 1; PRG-1; PRG1; 15-oxoprostaglandin 13-reductase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PTGR1; LTB4DH

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q14914

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The NADP(H)-dependent enzyme leukotriene 12-hydroxy dehydrogenase (LTB4DH) catalyzes double bond reductions and oxo-reductions in lipoxins (15-oxo-lipoxin A 4 ), leukotrienes (leukotriene B 4) and E/F prostaglandins (15-oxo prostaglandins). The reactions mediated by LTB4DH constitute an important inactivation pathway for these key lipid mediators involved in inflammation. LTB4DH belongs to the medium-chain dehydrogenase/reductase enzyme family.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LTB4DH (L105) polyclonal antibody detects endogenous levels of LTB4DH protein.

Bioworld Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of LTB4DH (L105) pAb at 1:500 dilution
Lane 1: The Kidney tissue lysate of Mouse(40ug)
Lane 2: HepG2 whole cell lysate(10ug)
Lane 3: HEK293T whole cell lysate(10ug)

Immunogen: Synthetic peptide, corresponding to amino acids 72-123 of Human LTB4DH.

Conjugate: Unconjugated

Modification: Unmodified