LTOR3 Polyclonal Antibody - BT-AP11000

LTOR3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11000-20, BT-AP11000-50, BT-AP11000-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.

Research Areas: Signal transduction

Target Protein: LAMTOR3

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Ragulator complex protein LAMTOR3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9UHA4; Mouse: O88653; Rat: Q5U204

Synonyms: Ragulator complex protein LAMTOR3;Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3;MEK-binding partner 1;Mp1;Mitogen-activated protein kinase kinase 1-interacting protein 1;Mito

GeneID: Human: 8649

Research Use Only