Lumican Polyclonal Antibody-BS90812

Lumican Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90812-50, BS90812-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P51884(Human)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC IHC FC

All Applications: WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: Lumican, a member of the small leucine-rich proteoglycans (SLRPs) family of proteins, is a keratan sulfate proteoglycan present in large quantities in the corneal stroma and in interstitial collagenous matrices of the heart, aorta, skeletal muscle, skin, and intervertebral discs. During collagen fibrillogenesis, lumican regulates the assembly of collagens into higher order fibrils, limiting the growth of fibrils in diameter. Lumican is present in the extracellular matrix of human articular cartilage at all ages, with a far greater abundance in the adult. The gene encoding human lumican maps to chromosome 12q21.3-q22.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: Lumican polyclonal antibody detects endogenous levels of Lumican protein.

Bioworld Molecular Weight: 38 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Lumican on different lysates using anti-Lumican antibody at 1/1,000 dilution.
Positive control:
Lane 1: Jurkat
Lane 2: 293T
Lane 3: Human skin, ICC staining Lumican in MG-63 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: KSPG lumican, LUM, LDC, SLRR2D, Keratan sulfate proteoglycan lumican, KSPG lumican, LDC, LUM, LUM, Lumican, Lumican precursor, SLRR2D,

Immunogen: Recombinant protein within human Lumican aa 50-250.

Conjugate: Unconjugated

Modification: Unmodified