Product Description

LYPD6B Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB67156-50, MB67156-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Believed to act as a modμlator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modμlates specifically alpha-33:beta-42 nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh, has no effect on alpha-7 homomeric nAChRs, modμlates alpha-32:alpha-5:beta-42 nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Mouse

Applications: WB

Alternate Names: Ly6/PLAUR domain-containing protein 6B

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LYPD6B. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/2000)

Specificity: Recognizes endogenous levels of LYPD6B protein.

Molecular Weight: ~ 27 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8NI32

Product: Mouse IgG2b. Supplied in crude ascites with 0.01% sodium azide.

Research Use Only