LYPD6B Monoclonal Antibody-MB67156

LYPD6B Monoclonal Antibody

Catalogue Numbers: MB67156-50, MB67156-100

Sizes: 50µl, 100µl

Product: Mouse IgG2b. Supplied in crude ascites with 0.01% sodium azide.

Swiss-Prot: Q8NI32

Host: Mouse

Reactivity: Human, Mouse

Applications: WB

All Applications: WB (1/500 - 1/2000)

Background: Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-33:beta-42 nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-32:alpha-5:beta-42 nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of LYPD6B protein.

Extra Notes: Western blot analysis of LYPD6B expression in mouse stomach (A) whole cell lysates.

Bioworld Molecular Weight: ~ 27 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Ly6/PLAUR domain-containing protein 6B

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LYPD6B. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified