Product Description

LYPLA1 (K90) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3063-50, BS3063-100

Sizes: 50µl, 100µl

Swiss-Prot: O75608

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Acyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids. APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia. Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LYPLA1 (K90) polyclonal antibody detects endogenous levels of LYPLA1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of LYPLA1 (K90) polyclonal antibody at 1:500 dilution
Lane 1: A549 whole cell lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat liver tissue lysate, Immunohistochemistry (IHC) analyzes of LYPLA1 (K90) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 25 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Acyl-protein thioesterase 1; APT-1; hAPT1; Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I; LYPLA1; APT1; LPL1

Immunogen: Synthetic peptide, corresponding to amino acids 61-110 of Human LYPLA1.

Conjugate: Unconjugated

Modification: Unmodified