Product Description

LYRIC (2E4) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3150-50, MB3150-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q86UE4

Host: Mouse

Reactivity: Human

Applications: WB, IHC-P, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100

Background: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 64 kDa; Observed MW: 64 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Lyric/Metadherin in Jurkat, A549, MCF-7 and Hela lysates using Lyric/Metadherin antibody., Flow cytometry analysis of Hela cells stained with Metadherin antibody and negative control., Immunohistochemistry analysis of paraffin-embedded Human Liver tissues using Metadherin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: MTDH; AEG1; LYRIC; Protein LYRIC; 3D3/LYRIC; Astrocyte elevated gene-1 protein; AEG-1; Lysine-rich CEACAM1 co-isolated protein; Metadherin; Metastasis adhesion protein

Immunogen: Purified recombinant fragment of human Metadherin expressed in E. Coli.

Conjugate: Unconjugated

Modification: Unmodified