Product Description

LYZ Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS7720-50, BS7720-100

Swiss-Prot: P61626

Host: Rabbit

LYZ Polyclonal Antibody-BS7720

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF, IP,

All Applications: WB 1:5000 - 1:10000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:20 - 1:50

Background: The origins of the lysozyme proteins date back an estimated 400 to 600 million years. Generally, lysozyme genes are relatively small, roughly 10 kilobases in length, and composed of four exons and three introns. Originally a bacteriolytic defensive agent, the function of this family of proteins adapted to serve a digestive function in its present forms. Lysozymes in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lysozyme C belongs to the glycosyl hydrolase 22 family, and newly identified relatives of Lysozyme C appear to possess anti-HIV activity, as well as preserved bacteriolytic function against Micrococcus lysodeikticus. Lysozyme C is capable of both hydrolysis and transglycosylation and also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides. Lysozyme C defects are a cause of amyloidosis VIII, also called familial visceral or Ostertag-type amyloidosis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LYZ polyclonal antibody detects endogenous levels of LYZ protein.

Bioworld Molecular Weight: ~ 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using LYZ antibody., Immunohistochemistry of paraffin-embedded mouse spleen using LYZ antibody.

Alternative Name: 1 4 beta N acetylmuramidase C;
1;
4-beta-N-acetylmuramidase C;
EC 3.2.1.17;
LYSC_HUMAN;
Lysosyme;
Lysozyme (renal amyloidosis);
Lysozyme C;
Lysozyme C precursor;
LYZ;
LZM;
Renal amyloidosis;

Immunogen: Recombinant full length Human LYZ.

Modification: Unmodified

Conjugate: Unconjugated