Product Description

LZTR1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60279-50, BS60279-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: LZTR1, leucine-zipper-like transcriptional regμlator 1, is a member of the BTBkelch superfamily. LZTR1 contains 2 BTB (POZ) domains and 6 Kelch repeats. The BTB (broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains mμltiple copies of kelch repeats and/or C2 H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regμlation via control of chromatin structure and function. LZTR1 is believed to function as a transcriptional regμlator during embryogenesis. LZTR1 is expressed in fetal brain, heart, kidney, liver and lung and is found exclusively on the cytoplasmic surface of the Golgi network. LZTR1 likely contributes to the etiology of velocardiofacial/DiGeorge syndrome, as the LZTR1 gene lies within a chromosomal deletion region associated with the disease.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Leucine-zipper-like transcriptional regμlator 1, LZTR-1, TCFL2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human LZTR1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: LZTR1 polyclonal antibody detects endogenous levels of LZTR1 protein.

Molecular Weight: ~ 95 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8N653

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only