M-RIP Polyclonal Antibody - BT-AP05559

M-RIP Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05559-20, BT-AP05559-50, BT-AP05559-100

Citations, Manuals and MSDS Available upon request.

Background: MPRIP (Myosin Phosphatase Rho Interacting Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding. Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Research Areas: Signal Transduction

Target Protein: MPRIP

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: M-RIP Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 116446

UniProt Accession: Human: Q6WCQ1; Mouse: P97434; Rat: Q9ERE6

Synonyms: MPRIP; KIAA0864; MRIP; RHOIP3; Myosin phosphatase Rho-interacting protein; M-RIP; Rho-interacting protein 3; RIP3; p116Rip

GeneID: Human: 23164/23164; Mouse: 26936; Rat: 116504

Research Use Only