Product Description

M-RIP Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27377-50, RA27377-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells., similarity:Contains 1 PH domain., similarity:Contains 2 PH domains., subcellular location:Colocalizes with F-actin., subunit:Binds F-actin through its N-terminus (By similarity). Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC-p, IF (paraffin section), WB, ELISA

Alternate Names: MPRIP, KIAA0864, MRIP, RHOIP3, Myosin phosphatase Rho-interacting protein, M-RIP, Rho-interacting protein 3, RIP3, p116Rip

Clonality: Polyclonal

Dilution: WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight: 110

Protein Molecular Weight (kDa): 110

Storage: -20°C/1 year

Human Gene ID: 23164

Human SwissProt Number: Q6WCQ1

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only