M3K14 Polyclonal Antibody - BT-AP11027

M3K14 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11027-20, BT-AP11027-50, BT-AP11027-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Research Areas: Cell biology; Signal transduction; Epigenetics and nuclear signaling

Target Protein: MAP3K14

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Mitogen-activated protein kinase kinase kinase 14

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q99558; Mouse: Q9WUL6

Synonyms: Mitogen-activated protein kinase kinase kinase 14;EC 2.7.11.25;NF-kappa-beta-inducing kinase;HsNIK;Serine/threonine-protein kinase NIK

GeneID: Human: 9020

Research Use Only