Product Description

M6PR Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40163-50, BS40163-100

Swiss-Prot: P11717

Host: Rabbit

M6PR Rabbit Monoclonal Antibody-BS40163

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP, FC

All Applications: WB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:100

Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

Purification and Purity: Affinity-chromatography

Specificity: M6PR Antibody detects endogenous levels of total M6PR

Bioworld Molecular Weight: 274kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of M6PR expression in Jurkat cell lysate., Immunohistochemical analysis of paraffin-embedded human colon, using M6PR Antibody.

Alternative Name: IGF2R; CI Man-6-P receptor; CI-MPR; M6PR; MPR 300; Insulin-like growth factor 2 receptor; M6P/IGF2R; CD222;

Immunogen: A synthesized peptide derived from human M6PR

Modification: Unmodified

Conjugate: Unconjugated