Mac-2BP rabbit pAb - ES8657

Mac-2BP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8657-50, ES8657-100

Citations, Manuals and MSDS Available upon request.

Background: The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008],

Alternate Name: Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000, ELISA 1:10000-20000

Reactivity: Human; Mouse

Immunogen: Synthetic peptide from human protein at AA range: 100-160

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 65kD

Human Gene ID: 3959

Human SWISS Prot NO: Q08380

Subcellular Location: Secreted. Secreted, extracellular space, extracellular matrix.

Research Use Only