Macro H2A.1 Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16887-50, BZ16887-100
Swiss-Prot: O75367
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 40 kDa; Observed MW: 40 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of macroH2A.1 in HepG2 lysates using Macro H2A.1 antibody.
Alternative Name: H2A.y; H2A/y; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2
Immunogen: A synthesized peptide derived from human macroH2A.1
Conjugate: Unconjugated
Modification: Unmodified