Product Description

MAD2L1BP Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5788-50, BS5788-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: MAD2L1BP (MAD2L1 binding protein), also known as CMT2, is a 274 amino acid protein that localizes to the nucleoplasm during early mitosis and to the spindle from metaphase through anaphase. Functioning as a component of the spindle checkpoint (which delays the onset of anaphase until kineotochore attachment is complete), MAD2L1BP is thought to coordinate cell cycle events in late mitosis, possibly binding to MAD2, thereby silencing the spindle checkpoint and allowing mitosis to proceed. MAD2L1BP is expressed as mμltiple alternative spliced isforms that, upon DNA damage, may be phosphorylated by ATM or ATR. The gene encoding MAD2L1BP maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: MAD2L1-binding protein, MAD2L1 binding protein, Caught by MAD2 protein, CMT2, KIAA0110

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 40-85 of Human MAD2L1BP.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MAD2L1BP polyclonal antibody detects endogenous levels of MAD2L1-binding protein protein.

Molecular Weight: ~ 34 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15013

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only