Product Description

MADCAM1 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS66129-50, BS66129-100

Swiss-Prot: Q13477

Host: Rabbit

MADCAM1 Polyclonal Antibody-BS66129

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB 1:200 - 1:1000
IHC 1:50 - 1:100

Background: The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MADCAM1 polyclonal antibody detects endogenous levels of MADCAM1 protein.

Bioworld Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using MADCAM1 antibody at 1:1000 dilution., Immunohistochemistry of paraffin-embedded human appendix using MADCAM1 antibody at dilution of 1:100 (40x lens) .

Alternative Name: MADCAM1; MACAM1

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MADCAM1 (NP_570116.2).

Modification: Unmodified

Conjugate: Unconjugated