Product Description

MADD Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67010-50, BS67010-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Guanyl-nucleotide exchange factor that regμlates small GTPases of the Rab family (PubMed:20937701, PubMed:18559336).Converts GDP-bound inactive form of RAB27A and RAB27B to the GTP-bound active forms (PubMed:20937701, PubMed:18559336).Converts GDP-bound inactive form of RAB3A, RAB3C and RAB3D to the GTP-bound active forms, GTPases involved in synaptic vesicle exocytosis and vesicle secretion (By similarity).Plays a role in synaptic vesicle formation and in vesicle trafficking at the neuromuscμlar junction (By similarity).Involved in up-regμlating a post-docking step of synaptic exocytosis in central synapses (By similarity).

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB

Alternate Names: DENN, IG20, KIAA0358, MAP kinase-activating death domain protein, Differentially expressed in normal and neoplastic cells, Insμlinoma glucagonoma clone 20, Rab3 GDP/GTP exchange factor

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MADD. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of MADD protein.

Molecular Weight: ~ 200 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8WXG6

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only