MAFB Polyclonal Antibody-BS71024

MAFB Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS71024-50, BS71024-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9Y5Q3

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: MafB is expressed in a wide variety of tissues and encodes a protein containing a typical bZip motif in its carboxy-terminal region. As a transcriptional activator, MafB plays a pivotal role in regulating lineage-specific gene expression during hematopoiesis by repressing Ets-1-mediated transcription of key erythroid-specific genes in myeloid cells. c-Maf interacts with the c-Myb DNA binding domain and forms Myb-Maf complexes, which inturn mediate the cooperative interactions between c-Myb and Ets-1 during early myeloid cell differentiation.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MAFB polyclonal antibody detects endogenous levels of MAFB protein.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cells, using MAFB antibody.

Alternative Name: Transcription factor MafB; Maf-B; V-maf musculoaponeurotic fibrosarcoma oncogene homolog B; MAFB; KRML

Immunogen: Recombinant protein of human MAFB.

Conjugate: Unconjugated

Modification: Unmodified