Product Description

MAGEA3 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11184-50, MB11184-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P43357

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MAGEA3 in HelaLysates using MAGEA3 antibody.

Bioworld Molecular Weight: Calculated MW: 35 kDa; Observed MW: 45 kDa

Specificity: IgG

Alternative Name: HIP8; HYPD; CT1.3; MAGE3; MAGEA6

Immunogen: Recombinant protein of human MAGEA3

Conjugate: Unconjugated

Modification: Unmodified