MAGEA9 Polyclonal Antibody
Catalogue Numbers: BS61025-50, BS61025-100
Sizes: 50µl, 100µl
Alternative Name: Melanoma-associated antigen 9; Cancer/testis antigen 1.9; CT1.9; MAGE-9 antigen; MAGEA9; MAGE9; MAGEA9A; MAGEA9B
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P43362
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types as well as in normal testis and placenta. MAGE-A9 (melanoma-associated antigen 9), also known as MAGE9 or CT1.9 (cancer/testis antigen 1.9), is a 315 amino acid protein that contains one MAGE domain. Like most MAGE family members, MAGE-A9 is expressed in several types of tumors, including lung cancer, breast cancer and melanoma, and is thought to play an important role in tumor progression and transformation. Additionally, MAGE-A9 may be involved in embryonic development.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MAGEA9 polyclonal antibody detects endogenous levels of MAGEA9 protein.
Bioworld Molecular Weight: ~ 35 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of MAGEA9 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T whole cell lysate
Lane 2: RAW264.7 whole cell lysate
Lane 3: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human MAGEA9.
Conjugate: Unconjugated
Modification: Unmodified