MAOB Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90821-50, BS90821-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P27338(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, IHC
All Applications: WB:1:500
IHC:1:50-1:200
Background: Monoamine oxidase (MAO) is an enzyme of the mitochondrial outer membrane and catalyzes the oxidative deamination of biogenic amines throughout the body. MAO is critical in the neuronal metabolism of catecholamine and indolamine transmitters. Cultured skin fibroblasts show both MAO-A and MAO-B and both MAOs differ in molecular structure. MAO-A, the primary type in fibroblasts, preferentially degrades serotonin and norepinephrine. Only MAO-B is present in platelets and only MAO-A is present in trophoblasts. MAO-B, the primary type found not only in platelets but also in the brain of man and other primates, preferentially degrades phenylethylamine and benzylamine. MAO has been of particular interest to psychiatry and genetics because of the suggestion that low activity is a 'genetic marker' for schizophrenia. The genes which encode MAO-A and MAO-B map to human chromosome Xp11.23.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: MAOB polyclonal antibody detects endogenous levels of MAOB protein.
Bioworld Molecular Weight: 59 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Monoamine Oxidase B on human liver tissue lysates using anti-Monoamine Oxidase B antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-Monoamine Oxidase B antibody. Counter stained with hematoxylin.
Alternative Name: MAO-B, MAOB, Adrenalin oxidase, Amine oxidase (flavin containing), Amine oxidase [flavin-containing] B, AOFB, MAO, brain, MAO, platelet, MAO-B, MAOB, MGC26382, Monoamine oxidase B, Monoamine oxidase type B, OTTHUMP00000023166, Tyramine oxidase,
Immunogen: Recombinant protein within human Monoamine Oxidase B aa 1-200.
Conjugate: Unconjugated
Modification: Unmodified