MAP2K6 (8A11) Monoclonal Antibody-MB3092

MAP2K6 (8A11) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3092-50, MB3092-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P52564

Host: Mouse

Reactivity: Human, Rat

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 37 kDa; Observed MW: 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MAP2K6 in PC-12, C6, Ramos, Jurkat and Hela lysates using MKK3/6 antibody., Immunoprecipitation analysis of MAP2K6 in Hela lysates using MKK3/6 antibody.

Alternative Name: MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3

Immunogen: Purified recombinant human MKK6 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified