Product Description

MAPK6 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11187-50, MB11187-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q16659

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle .

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 83 kDa; Observed MW: 105 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MAPK6 in 3T3, Hela lysates using MAPK6 antibody., Immunohistochemistry analysis of paraffin-embedded Human colon cancer using MAPK6/ERK3 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: ERK3; PRKM6; p97MAPK; HsT17250; ERK-3

Immunogen: A synthetic peptide of human MAPK6

Conjugate: Unconjugated

Modification: Unmodified