Product Description

MAPK9 (JNK2) Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4366-25, MB4366-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for mμltiple biochemical signals, and are involved in a wide variety of cellμlar processes such as proliferation, differentiation, transcription regμlation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimμli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]

Category: Primary Antibody

Reactivity: Human, Dog, Rat, Monkey, Mouse

Host: Mouse

Applications: IF, IHC, WB

Alternate Names: JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, p54a, p54aSAPK, PRKM9, SAPK, SAPK1a

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Fμll length human recombinant protein of human MAPK9(NP_620707) produced in HEK293T cell.

Dilution: WB 1:200~2000, IHC 1:150, IF 1:100

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1

Molecular Weight: 43.9 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P45984

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only