MARCH2 Polyclonal Antibody - BT-AP05214

MARCH2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05214-20, BT-AP05214-50, BT-AP05214-100

Citations, Manuals and MSDS Available upon request.

Background: MARCH2 (membrane associated ring-CH-type finger 2) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking.

Research Areas: Cell Biology

Target Protein: MARCH2

Applications: IHC-p, IF, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: 44257 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 26995

UniProt Accession: Human: Q9P0N8; Mouse: Q99M02

Synonyms: MARCH2; RNF172; HSPC240; E3 ubiquitin-protein ligase MARCH2; Membrane-associated RING finger protein 2; Membrane-associated RING-CH protein II; MARCH-II; RING finger protein 172

GeneID: Human: 51257

Research Use Only