MARCKS (Phospho-Ser159/163) Rabbit Polyclonal Antibody - BT-AP11241

MARCKS (Phospho-Ser159/163) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11241-20, BT-AP11241-50, BT-AP11241-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility| phagocytosis| membrane trafficking and mitogenesis.

Research Areas: Cardiovascular; Signal transduction

Target Protein: MARCKS

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MARCKS

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P29966; Mouse: P26645; Rat: P30009

Synonyms: MARCKS;Ser159/163; Myristoylated alanine-rich C-kinase substrate; MARCKS; Protein kinase C substrate; 80 kDa protein; light chain; 80K-L protein; PKCSL

GeneID: Human: 4082; Mouse: 17118

Research Use Only