MARK1/2/3/4 (phospho Thr215) rabbit pAb - ES6191

MARK1/2/3/4 (phospho Thr215) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6191-50, ES6191-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Activated by phosphorylation on Thr-215 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39., function:May play a role in cytoskeletal stability., similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily., similarity:Contains 1 KA1 (kinase-associated) domain., similarity:Contains 1 protein kinase domain., similarity:Contains 1 UBA domain., subcellular location:Appears to localize to an intracellular network., tissue specificity:Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney.,

Alternate Name: MARK1; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affin

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MARK1/2/3/4 around the phosphorylation site of Thr215. AA range:181-230

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4139/2011/4140/57787

Human SWISS Prot NO: Q9P0L2/Q7KZI7/P27448/Q96L34

Subcellular Location: Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, dendrite. Appears to localize to an intracellular network.

Research Use Only