MARVELD1 Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65955-50, BS65955-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity. Category: Primary Antibody Reactivity: Human, Mouse, Rabbit Host: Rabbit Applications: WB Alternate Names: GB14, MARVD1, MARVEL (membrane-associating) domain containing 1, MARVEL domain containing protein 1, MRVLDC1, Putative MARVEL domain containing protein 1, MALD1_HUMAN. Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human MARVELD1:31-130/173 Dilution: WB=1:500-2000 Purification: affinity purified by Protein A Specificity: MARVELD1 Polyclonal Antibody detects endogenous levels of MARVELD1 protein. Molecular Weight: 19 kD Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: Q9BSK0 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only