MAST205 rabbit pAb - ES2749

MAST205 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2749-50, ES2749-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., function:Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation., PTM:Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 PDZ (DHR) domain., similarity:Contains 1 protein kinase domain., subcellular location:Recruited to the sub-membranous area on interaction with PC-LKC., tissue specificity:Abundant in the testis.,

Alternate Name: MAST2; KIAA0807; MAST205; Microtubule-associated serine/threonine-protein kinase 2

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human MAST2. AA range:1201-1250

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 196kD

Human Gene ID: 23139

Human SWISS Prot NO: Q6P0Q8

Subcellular Location: Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Recruited to the sub-membranous area on interaction with CDHR2.

Research Use Only