MATER Polyclonal Antibody-BS90826

MATER Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90826-50, BS90826-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P59047

Host: Rabbit

Reactivity: Human, mouse

Applications: ICC

All Applications: ICC:1:200

Background: NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals. Conserved oocyte-specific expression of NLRP5 is consistent among many mammalian species. As a member of the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress beyond the first embryonic cell divisions. NLRP5 also localizes to the nuclear envelope and mitochondria in germinal vesicle oocytes, suggesting a possible role in mitochondrial function.

Purification and Purity: Peptide affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining MATER in mouse blastocyst and 2-cell stage embryo (red). Cells were incubated overnight at 4°C with MATER rabbit pAb at 1/100 dilution (shown in red) and phalloidin antibody (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).

Bioworld Molecular Weight: 134 kDa

Specificity: MATER polyclonal antibody detects endogenous levels of MATER protein.

Alternative Name: MATER, NALP5, CLR19.8, MATER, Mater protein homolog, Maternal antigen that embryos require, NACHT, leucine rich repeat and PYD containing 5, NACHT, LRR and PYD domains-containing protein 5, NALP5, NLR family, pyrin domain containing 5, NLRP5, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5, PAN11, PYPAF8,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodified