Product Description

MaxiKβ (K119) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3554-50, BS3554-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: MaxiK channels are large conductance voltage and Ca 2+-activated potassium channels which are formed by tetramers of MaxiKα subunits, which create pores that are used for smooth muscle tone and neuronal excitability. These MaxiKα subunits have the ability to coassemble with MaxiKβ subunits that are structurally related and are able to regμlate the function of MaxiKα subunits. KCNMB4 (potassium large conductance calcium-activated channel, subfamily M, β member 4), also known as Slo-β-4 or Maxi K channel subunit β-4, is a 210 amino acid mμlti-pass membrane protein belonging to the KCNMB family. Predominantly expressed in brain, KCNMB4 is a regμlatory subunit of the calcium activated potassium MaxiKα channel. KCNMB4 contributes to MaxiKα channel diversity by modμlating calcium sensitivity and gating kinetics of MaxiKα.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Calcium-activated potassium channel subunit beta-4, BK channel subunit beta-4, BKbeta4, Hbeta4, Calcium-activated potassium channel, subfamily M subunit beta-4, Charybdotoxin receptor subunit beta-4, K(VCA)beta-4, Maxi K channel subunit beta-4, Slo-beta-4, KCNMB4

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 86-140 of Human MaxiKβ.

Dilution: IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MaxiKβ (K119) polyclonal antibody detects endogenous levels of MaxiKβ protein.

Molecular Weight: ~ 24 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q86W47

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only