MaxiKBeta Polyclonal Antibody - BT-AP05252

MaxiKBeta Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05252-20, BT-AP05252-50, BT-AP05252-100

Citations, Manuals and MSDS Available upon request.

Background: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. Calcium-activated potassium channel subunit beta-4 encoded by KCNMB4 is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.

Research Areas: Neuroscience

Target Protein: KCNMB4

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MaxiKbeta Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 23949

UniProt Accession: Human: Q86W47; Mouse: Q9JIN6; Rat: Q9ESK8

Synonyms: KCNMB4; Calcium-activated potassium channel subunit beta-4; BK channel subunit beta-4; BKbeta4; Hbeta4; Calcium-activated potassium channel; subfamily M subunit beta-4; Charybdotoxin receptor subunit

GeneID: Human: 27345; Mouse: 58802; Rat: 66016

Research Use Only