MBTPS1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-64597-60, E-AB-64597-120, E-AB-64597-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MBTPS1
Target Synonym: MBTPS1; PCSK8; S1P; SKI-1
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q14703
Background: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human MBTPS1 (NP_003782.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only