MC1-R (V312) Polyclonal Antibody-BS2735

MC1-R (V312) Polyclonal Antibody

Catalogue Numbers: BS2735-50, BS2735-100

Sizes: 50µl, 100µl

Alternative Name: Melanocyte-stimulating hormone receptor; MSH-R; Melanocortin receptor 1; MC1-R; MC1R; MSHR

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q01726

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:500~1:1000
IF: 1:50~1:200

Background: The melanocortin family comprises the α-, β- and γ-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MC1-R (V312) polyclonal antibody detects endogenous levels of MC1-R protein.

Bioworld Molecular Weight: ~ 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of MC1-R (V312) polyclonal antibody at 1:1000 dilution
Lane 1: Hela whole cell lysate(40ug)
Lane 2: The Brain tissue lysate of Rat(40ug)
Lane 3: The Brain tissue lysate of Mouse(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human MC1-R.

Conjugate: Unconjugated

Modification: Unmodified