MC2R Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A3010-20, A3010-100
Citations, Manuals and MSDS Available upon request.
Background: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC) . MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 34kDa
Observed Molecular Weight: 37kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 4158
SWISS: Q01718
Alternate Names: ACTHR; MC2R
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Endocrine Metabolism, Lipid Metabolism, Cholesterol Metabolism, Neuroscience, Cardiovascular, Lipids.
NCBI Alias: MC2R
Research Use Only