MCAD Polyclonal Antibody - BT-AP05266

MCAD Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05266-20, BT-AP05266-50, BT-AP05266-100

Citations, Manuals and MSDS Available upon request.

Background: ACADM encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal Transduction; Metabolism

Target Protein: ACADM

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: MCAD Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 46588

UniProt Accession: Human: P11310; Mouse: P45952; Rat: P08503

Synonyms: ACADM; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD

GeneID: Human: 34; Mouse: 11364; Rat: 24158

Research Use Only