Product Description

MCL1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16447-50, BZ16447-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q07820

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: MCL1 a myeloid cell leukemia protein of the Bcl-2 family of proteins. Two alternatively spliced transcripts encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 37 kDa; Observed MW: 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MCL1 in various lysates using MCL1 antibody., Western blot analysis of MCL1 in Jurkat lysates using Mcl1 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using MCL1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Western blot analysis of MCL1 in HUVEC lysates using MCL1 antibody. The Lane on the right is blocked with the synthesized peptide.

Alternative Name: MCL1; BCL2L3; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EAT

Immunogen: The antiserum was produced against synthesized peptide derived from human MCL1. AA range:91-140

Conjugate: Unconjugated

Modification: Unmodified