Product Description

MCM2 Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB67305-25, MB67305-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regμlate the helicase activity of the complex. This protein is phosphorylated, and thus regμlated by, protein kinases CDC2 and CDC7. Mμltiple alternatively spliced transcript variants have been found, but the fμll-length nature of some variants has not been defined.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IHC

Alternate Names: BM28, CCNL1, cdc19, CDCL1, D3S3194, MITOTIN

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Fμll length human recombinant protein of human MCM2 (NP_004517) produced in HEK293T cell.

Dilution: WB 1:500, IHC 1:150

Purification: Purified from mouse ascites fluids or tissue cμlture supernatant by affinity chromatography (protein A/G)

Specificity: MCM2 mouse monoclonal antibody detects endogenous levels of MCM2 protein.

Molecular Weight: ~ 120 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: OTI8A11

Product: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Research Use Only