MCM2 (phospho-Ser139) Rabbit Polyclonal Antibody - RA27088

MCM2 (phospho-Ser139) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27088-50, RA27088-100

Citations, Manuals and MSDS Available upon request.

Background: minichromosome maintenance complex component 2 (MCM2) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4171

Protein MW (KDa): 120

SWISS: P49736

Source: Rabbit

Research Use Only