MCM3 (phospho-Ser112) Rabbit Polyclonal Antibody - RA27089

MCM3 (phospho-Ser112) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27089-50, RA27089-100

Citations, Manuals and MSDS Available upon request.

Background: minichromosome maintenance complex component 3 (MCM3) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)

Applications: WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 4172

Protein MW (KDa): 89

SWISS: P25205

Source: Rabbit

Research Use Only