MCM7 Monoclonal Antibody-MB11195

MCM7 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11195-50, MB11195-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P33993

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 81 kDa; Observed MW: 81 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of MCM7 in 3T3 lysates using MCM7 antibody., Western blot analysis of MCM7 in K562, C6, Hela lysates using MCM7 antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using MCM7 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: MCM7; CDC47; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; P1.1-MCM3

Immunogen: A synthetic peptide of human MCM7

Conjugate: Unconjugated

Modification: Unmodified