
MCM7 Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16864-50, BZ16864-100
Swiss-Prot: P33993
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, ICC/IF, IP, FC
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 81 kDa; Observed MW: 81 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of MCM7 in Hela lysates using MCM7 antibody.
Alternative Name: MCM7; CDC47; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; P1.1-MCM3
Immunogen: A synthesized peptide derived from human MCM7
Conjugate: Unconjugated
Modification: Unmodified